Melanosis Wikipedia This lovely patient was thrilled with her beautiful result after laser treatment of oral melanotic macules. I share this case to educate: laser treatment requires accurate diagnosis, an understanding of the differential Oral Melanotic Macule: Symptoms and Treatment Skinsight Melanosis coli: Symptoms, causes, treatment, and more Neurocutaneous Melanosis (Neurocutaneous melanocytosis) Dermatology Advisor