HMP Pathway Simplified: NADPH Role & G6PD Deficiency Explained The Pentose Phosphate Pathway & G6PD Deficiency , Blog: https: bit.ly pentosephosphatepathway; https: bit.ly g6pddeficiency, YouTube: https: youtu.be ITy2gkUD7eM , Key points about the Pentose G6PD Deficiency causes Haemolytic Anaemia Glucose 6 phosphate dehydrogenase is an enzyme in the hexose monophosphate shunt that synthesizes NADPH. The NADPH is used to convert oxidized glutathione (GSSG) to reduced glutathione ( Figure 2 from Impact of glucose 6 phosphate dehydrogenase deficiency on the pathophysiology of cardiovascular disease. Semantic Scholar Glucose 6 Phosphate Dehydrogenase an overview ScienceDirect Topics