Intramuscular Injections Vitamin B12 Side Effects B12 Injection Dosage and Frequency: 7 Essential Guidelines for Adults Liv Hospital High dose vitamin B12 supplements can sometimes cause side effects, including headache, nausea, vomiting, mild diarrhea, itching, skin rash, tiredness, weakness, or tingling in the hands and feet. OC: B12 Shots: Vitamin B12 Injections Benefits, Uses, Risks Dr. Axe
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